Department of Biotechnology, Chaitanya Bharathi Institute of Technology, Gandipet, Hyderabad.
The nanotoxic effect of metallic nanoparticles such as iron, gold, and copper
nanoparticles was investigated using Escherichia coli, Bacillus subtilis Staphylococcus
aureus, and Pseudomonas aeruginosa. The average sizes of the nanoparticles ranged
from 35nm to 75nm were used for the present investigation. The antimicrobial effect of
iron, gold, and copper nanoparticles was compared based on the diameter of the
inhibition zone in disc diffusion tests. Bacterial sensitivity to metallic nanoparticles was
found to vary depending on the microbial species. Disk diffusion studies with P.
aeruginosarevealed greater effectiveness of the compared other strains for iron and
copper nanoparticles. Bacillus subtilis depicted the highest resistance to gold
nanoparticles compared to the other strains.
Among the three different nanoparticles, iron nanoparticles showed the highest