ISSN: 1007-1172

Impact Factor: 6.2


Journal of Shanghai Jiaotong University

International Peer Reviewed | Open Access | A Monthly Publishing Journal

"Interaction and Nanotoxic Effect of Metallic Nanoparticles on Bacterial Strains"


Varimadugu Aruna
Department of Biotechnology, Chaitanya Bharathi Institute of Technology, Gandipet, Hyderabad.


The nanotoxic effect of metallic nanoparticles such as iron, gold, and copper nanoparticles was investigated using Escherichia coli, Bacillus subtilis Staphylococcus aureus, and Pseudomonas aeruginosa. The average sizes of the nanoparticles ranged from 35nm to 75nm were used for the present investigation. The antimicrobial effect of iron, gold, and copper nanoparticles was compared based on the diameter of the inhibition zone in disc diffusion tests. Bacterial sensitivity to metallic nanoparticles was found to vary depending on the microbial species. Disk diffusion studies with P. aeruginosarevealed greater effectiveness of the compared other strains for iron and copper nanoparticles. Bacillus subtilis depicted the highest resistance to gold nanoparticles compared to the other strains. Among the three different nanoparticles, iron nanoparticles showed the highest antimicrobial activity.